The "Poison in the Roots" quest in Diablo 4 Season 7 is crucial for unlocking new Witchcraft powers. If you're struggling with the puzzles or enemy waves, this guide will provide step-by-step solutions and combat tips. Need an extra edge? U4GM offers Diablo 4 Items so you can gear up instantly.

Step 1: Begin the Quest at the Tree of Whispers
Gather Grim Favors to start the quest.
Meet the three witches who will guide you through the ritual.
Step 2: Solve the Brazier Puzzle
Light the braziers in this exact sequence:

Ayh (Bottom Left)
Yew (Bottom Right)
Oun (Top)
Step 3: Gathering and Using Nangri Blood
Defeat the three summoned snakes to collect Nangri Blood.
Walk around the ritual circle to spread the blood and trigger the next phase.
Step 4: Defend the Ritual from Enemy Waves
Stay inside the circle to prevent enemies from interfering.
Use wide-range attacks to eliminate multiple foes at once.
If playing a Necromancer, let minions block enemy paths while you attack safely.
Claim Your Legendary Rewards
Once the ritual is complete, you’ll receive a Legendary Cache. For faster character progression, U4GM offers buy Diablo 4 Boosting and high-quality items, ensuring you’re always ready for the toughest fights in Season 7.